In bottom mixing embodiment, 16 represents the disgorging ports of surface feedlines configured such that the feed does not run down the side of the bioprocess container, in an aspect of the disclosure, at least 3 feed lines discharging above the surface of the culture are required. Amgen yet another embodiment, the clamp is a amgen bioreactor bottom mixing steel2 part high bioreactor clamp with nut and bolt. This is time consuming and expensive. In one embodiment, the bioreactor can contain from about one to about five, such as from about two to about three feed lines that have a supersurface fluid discharge.
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Stainless Steel Hard Wall GMP Agitated Bioreactors & Fermenters
For instance, the bioprocess container can include a drain line located at the bottom of the bioprocess container. The plurality of holes have a diameter. The bioreactor can further include at least one sparger. The baffle can have a shape that extends radially inward from the side wall in an amount sufficient to affect fluid flow in the hollow enclosure during mixing of a culture medium by amgen bioreactor bottom mixing mixing device.
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Spin filters can also be used, such as when the device is operating in perfusion mode. It is a further object of the disclosure to provide single-use bioreactors featuring enhanced operating characteristics. The bioreactor can also include at least one baffle configured to extend adjacent to the side wall of the bioprocess container in a longitudinal direction. In some embodiments, the cover includes at least one ports, such amgen bioreactor bottom mixing at least two ports, such as at least three ports, such as at least four ports, such as at least five ports. In still other embodiments, the polymer material may be subjected to corona discharge.